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§34 · 13 tips

Don't get hurt by the medicine cabinet at home

When you buy cold, fever and stomach medicine yourself, which ones can't be taken together, and what should children, pregnant women and older people avoid?

Tips from this section that apply in the United States. This section is about health and medicines. It is general information, not a substitute for a doctor’s diagnosis or prescription.

Don't get hurt by the medicine cabinet at home

Before taking two cold medicines or two painkillers together, read the ingredient list; acetaminophen (paracetamol) should come from only one of them, and if you took too much, go to the hospital the same day even if you feel fine

Many cold medicines contain acetaminophen (paracetamol, 对乙酰氨基酚). Taking two boxes together means a double dose, and too much damages the liver. In the U.S., of the acute liver failure patients it causes, nearly 30% died before they could get a liver transplant. Chinese package inserts advise taking no more than 2 g a day, and the U.S. also warns not to drink 3 or more alcoholic drinks a day while using it. If you took too much, go to the hospital right away even if you feel fine; the earlier the antidote is given, the better.

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Don't get hurt by the medicine cabinet at home

Don't use aspirin, nimesulide (尼美舒利) or metamizole (安乃近) for a child's fever, don't give minors cold medicines that contain metamizole, and measure liquid fever reducers with the dosing device that comes in the box

For a child's fever, don't use any of these three drugs. Aspirin is linked to Reye's syndrome (瑞氏综合征), a disease that damages the brain and liver; about 30% of the children with it died. Nimesulide (尼美舒利) is banned at age 12 and younger, and metamizole (安乃近) is banned at age 18 and younger. Measure liquid fever reducers with the dosing device that comes in the box; spoons at home vary widely in size. Drops and oral liquids can have different strengths, differing 3-fold in a U.S. example, so if you switch the form, don't keep giving the same number of milliliters.

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  • For: Child under 3, Child aged 3–18
Don't get hurt by the medicine cabinet at home

If you are 60 or older, have had stomach bleeding, or take blood thinners or steroids, ask a doctor before taking painkillers like ibuprofen

Painkillers such as ibuprofen, naproxen and aspirin can damage the stomach. In trials at high doses, people taking ibuprofen had about 4 times the risk of stomach bleeding or perforation of those not taking it. People who are older, have had stomach bleeding, take blood thinners or steroids at the same time, or have 3 or more alcoholic drinks a day are at higher risk.

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Don't get hurt by the medicine cabinet at home

Don't give a child aged 2 or younger combination cold medicines or cough medicines on your own for a cold

The National Medical Products Administration (国家药监局) required 14 combination cold medicines for children to carry a warning: parents are advised not to give them to children aged 2 or younger on their own, and they should be used only under the guidance of a doctor or pharmacist. In trials in children, cough medicines and antihistamines (allergy drugs) worked no better than placebo.

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  • For: Child under 3
Don't get hurt by the medicine cabinet at home

After 20 weeks of pregnancy, don't take painkillers like ibuprofen on your own

After 20 weeks of pregnancy, taking ibuprofen-type drugs may harm the baby's kidneys and reduce the amniotic fluid. Among the reports received in the U.S., there were cases of newborn death. Low-dose aspirin prescribed by a doctor is not included.

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  • For: Pregnant or trying
Don't get hurt by the medicine cabinet at home

If you buy omeprazole yourself for acid reflux and heartburn, take it for 7 days at most; go straight to the hospital for trouble swallowing, vomiting blood or black stools

Omeprazole enteric-coated tablets (奥美拉唑肠溶片) have been available without a prescription since 2022, but the insert says to take them yourself for no more than 7 days and not to take them again within two months. If you have trouble or pain swallowing, vomit blood, or have blood in the stool or black stools, don't take them on your own; these can be signs of a serious condition. The drug may also cover up the symptoms of stomach cancer and delay diagnosis.

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Don't get hurt by the medicine cabinet at home

Don't ask a doctor for antibiotics for an ordinary cold

Taking antibiotics for a cold doesn't make you better any faster than not taking them. Adults who took them had more than twice the risk of side effects of those who didn't. For a runny nose with pus lasting under 10 days, antibiotics also have no definite benefit.

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Don't get hurt by the medicine cabinet at home

For diarrhea, first drink oral rehydration salts to replace fluid, and don't give anti-diarrhea drugs to children aged 5 or younger

The most important thing in diarrhea is replacing fluid, not stopping the diarrhea. Mix oral rehydration salts (口服补液盐) with water as the instructions say and drink it; don't substitute fruit juice or soft drinks, because too much sugar actually makes you more dehydrated. Don't give anti-diarrhea drugs such as loperamide to children aged 5 or younger, because in serious cases they can cause a bowel obstruction that can be fatal.

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Don't get hurt by the medicine cabinet at home

Don't take painkillers on more than 15 days a month, or combination painkillers on more than 10 days, or the headache may be caused by the medicine itself

If you have frequent headaches and take painkillers every day, the headaches may get worse the more you take. The international headache classification calls this medication-overuse headache. Having headaches on 15 or more days a month, and taking ordinary painkillers on 15 or more days or combination painkillers on 10 or more days, for more than 3 months in a row, is enough to qualify. Most people improve after stopping the overused drug.

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Don't get hurt by the medicine cabinet at home

Clear out expired and unused leftover medicines on a regular schedule, and drop them with their packaging into the hazardous waste bin; don't keep them at home

Among medicines young children swallow by mistake behind adults' backs, nearly half are prescription tablets. About 30% of the prescription medicines swallowed by mistake belonged to grandparents. Clearing out medicines you don't need leaves one less thing a child can find. Put the cleared-out medicines, packaging and all, in the hazardous waste bin (有害垃圾), or hand them to a drugstore that collects old medicines.

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Don't get hurt by the medicine cabinet at home

Don't drink alcohol while taking antibacterial drugs like cephalosporins or metronidazole, or for 7 days after stopping, and don't touch alcohol-containing medicines such as Huoxiang Zhengqi liquid (藿香正气水) or cough syrup

When some cephalosporins (头孢), metronidazole (甲硝唑) and similar drugs meet alcohol, they can cause flushing, sweating and a pounding heart, and in serious cases trouble breathing and a drop in blood pressure. It is not only liquor and beer: alcohol-containing medicines such as Huoxiang Zhengqi liquid (藿香正气水) and cough syrup can set it off too. Stay away from alcohol during the medicine and for 7 days after stopping.

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Don't get hurt by the medicine cabinet at home

If you have taken a cold medicine or allergy medicine that contains chlorpheniramine (扑尔敏) or diphenhydramine, don't drive, work at heights or operate machines while taking it

Many combination cold medicines have allergy ingredients such as chlorpheniramine (扑尔敏) or diphenhydramine mixed in, and they make you drowsy. The National Medical Products Administration (国家药监局) advises not to drive, work at heights or operate machines while taking this kind of medicine. On a driving simulator, people who took diphenhydramine drove worse than after drinking alcohol. Not feeling sleepy does not mean you drive without problems.

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Don't get hurt by the medicine cabinet at home

If you take a medicine long term, such as a cholesterol or blood pressure drug, check the leaflet for grapefruit; if it is mentioned, don't eat grapefruit or pomelo and don't drink grapefruit juice

Grapefruit can make some drugs rise in the blood to several times their usual level, which is like taking too much even though the amount you take hasn't changed. One grapefruit or one glass of grapefruit juice is enough to do this, and taking the drug a day later still leaves some of the effect. In serious cases it can damage muscle or kidneys, or cause a heart rhythm disorder that can lead to sudden death. Pomelo has the same effect; ordinary sweet oranges do not.

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